How does urine get diluted




















There are two types of dilute specimens: positive and negative. With a positive diluted drug test, the laboratory picks up the presence of an illegal substance despite its dilution. Negative diluted drug test results are another story.

With a negative diluted test result, it is unknown whether the person had any drugs in their system because there are two possible conclusions. First, the participant may be drug-free but simply consume a lot of fluids. Second, the participant may engage in drug use but successfully disguise this through dilution. For this reason, an employer should not consider a negative diluted drug test result grounds for rejecting a job applicant or firing an employee. Instead, they should schedule a second drug test and do their best to prevent dilution the second time around.

To prevent both accidental and intentional dilution of drug test results, employers, participants, and testing centers are encouraged to use the following tips:. We can help you further explore your options so that you can select a testing methodology that reflects your wants, your needs, your concerns, and your budget.

The kidneys remove waste from the body by making urine. Additionally, testers can determine if the urine is diluted by referring to measurements called validity checks.

These checks include urine creatinine and specific gravity. Your kidneys remove creatinine through the urine. The amount of creatinine in your urine indicates its concentration. Urine specific gravity indicates the concentration of urine. It compares the water content to the amount of substances in the urine. Normal urine has a specific gravity of between 1. If the urine is diluted, the specific gravity is between 1. An immunoassay IA is a drug test that uses antibodies to detect the presence of certain drugs.

Antibodies are proteins that bind with antigens, or foreign substances. In this case, the antigen is the drug. In an IA, the tester adds the drug and drug-specific antibodies to the urine. If the drug is already in the urine, it will compete with the added drug to bind with the antibodies. This reaction means the sample is positive. The sample will be considered negative.

An IA is inexpensive and quick. This means it can yield false positive or false negative results. In GC-MS, a gas is added to the urine sample. The gas interacts with the substances in the urine, causing them to separate. The tester uses a machine called a mass spectrometer to detect the separate compounds.

GC-MS is the standard test used for follow-ups. Other types of chromatography may use liquid to separate the compounds. Diluted drug test results make it difficult to determine if the participant is using drugs, as they may provide inconclusive results.

There are two types of dilute specimens: positive and negative. With a positive diluted drug test, the laboratory picks up the presence of an illegal substance despite its dilution.

With a negative diluted test result, it is unknown whether the person had any drugs in their system because there are two possible conclusions. First, the participant may be drug-free but simply consume a lot of fluids. Second, the participant may engage in drug use but successfully disguise this through dilution.

Your email address will not be published. Tips to avoid Negative Dilute Drug Tests Not drinking excessive water which may lead to false negative result as well as sample rejection Advise the client to have 1st morning urine because it is concentrated urine.



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